Introduction to Epigenetic Profiling Epigenetic profiling is essential for elucidating gene regulation and chromatin dynamics. Chromatin Immunoprecipitation sequencing (ChIP-seq) has long been the gold standard for mapping protein-DNA interactions and histone modifications. However, the recent advent of Cleavage Under Targets and Release Using Nuclease (Cut&Run) has introduced a powerful alternative technique, offering several advantages over traditional ChIP-seq methodologies. […]
Written by kikogarcia
Overview of DAP-seq The DNA Affinity Purification Sequencing (DAP-seq) technique is an innovative method aimed at exploring the interactions between transcription factors (TFs) and genomic DNA. By simulating the interaction between TFs and their DNA binding sites in vitro, this technology reveals key DNA sequences in gene regulatory networks. In contrast to traditional Chromatin Immunoprecipitation Sequencing (ChIP-seq), DAP-seq is […]